Standardized determination of GFR by means of mathematical formulations in the whole population may yield low GFR values with unclear usefulnees in clinical practice.Īn example of the low reliability of these mathematical formulations is their indiscriminate use in the elderly. The simple calculation of the glomerular filtration rate (GFR) from mathematical formulations using the serum creatinine value (sCr), sometimes even being directly provided by the Laboratory, and the convenience of not having to collect 24-hour urine, has allowed health professionals to classify chronic renal disease (CRD) in several stages.
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